Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | DBH | P09172 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9962964 | 0.85 | GAA (0.56) | KDM4EDBHGAARECQLFFAR1 | |
| SCHEMBL22549048 | 0.78 | GAA (0.50) | KDM4EDBHGAARECQLFFAR1 | |
| SCHEMBL16256439 | 0.76 | KDM4E (0.54) | KDM4EDBHGAARECQLFFAR1 | |
| SCHEMBL20630226 | 0.76 | KDM4E (0.48) | KDM4EDBHGAARECQLFFAR1 | |
| SCHEMBL13921549 | 0.76 | KDM4E (0.48) | KDM4EDBHGAARECQLFFAR1 | |
| SCHEMBL23476588 | 0.76 | KDM4E (0.48) | KDM4EDBHGAARECQLFFAR1 | |
| SCHEMBL9965888 | 0.76 | KDM4E (0.48) | KDM4EDBHGAARECQLFFAR1 | |
| SCHEMBL24671657 | 0.74 | RECQL (0.47) | KDM4EDBHGAARECQLFFAR1 | |
| SCHEMBL22548929 | 0.73 | GAA (0.50) | KDM4EDBHGAARECQLFFAR1 | |
| SCHEMBL22548781 | 0.73 | KDM4E (0.45) | KDM4EDBHGAARECQLFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9193678-B2 | Chemical agents capable of forming covalent 3-D networks | OXFORD ADVANCED SURFACES LTD (GB) | 2015-11-24 | — | — | US | disclosed |
| US-20120021223-A1 | CHEMICAL AGENTS CAPABLE OF FORMING COVALENT 3-D NETWORKS | OXFORD ADVANCED SURFACES LTD. (GB) | 2012-01-26 | — | — | US | disclosed |