Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | DBH | P09172 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22549048 | 0.92 | GAA (0.50) | GAAKDM4EDBHRECQLFFAR1 | |
| SCHEMBL16256439 | 0.89 | KDM4E (0.54) | GAAKDM4EDBHRECQLFFAR1 | |
| SCHEMBL13921549 | 0.89 | KDM4E (0.48) | GAAKDM4EDBHRECQLFFAR1 | |
| SCHEMBL20630226 | 0.89 | KDM4E (0.48) | GAAKDM4EDBHRECQLFFAR1 | |
| SCHEMBL9965888 | 0.89 | KDM4E (0.48) | GAAKDM4EDBHRECQLFFAR1 | |
| SCHEMBL23476588 | 0.89 | KDM4E (0.48) | GAAKDM4EDBHRECQLFFAR1 | |
| SCHEMBL24671657 | 0.87 | RECQL (0.47) | GAAKDM4EDBHRECQLFFAR1 | |
| SCHEMBL22548781 | 0.85 | KDM4E (0.45) | GAAKDM4EDBHRECQLFFAR1 | |
| SCHEMBL10246468 | 0.85 | KDM4E (0.45) | GAAKDM4EDBHRECQLFFAR1 | |
| SCHEMBL22548929 | 0.85 | GAA (0.50) | GAAKDM4EDBHRECQLFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746126-B2 | Bicyclic peptide ligands with detectable moieties and uses thereof | Bicyclerd Limited (GB) | 2023-09-05 | — | — | US | disclosed |
| US-11746126-B2 | Bicyclic peptide ligands with detectable moieties and uses thereof | Bicyclerd Limited (GB) | 2023-09-05 | — | — | US | disclosed |
| US-20210147484-A1 | BICYCLIC PEPTIDE LIGANDS AND USES THEREOF | BICYCLETX LIMITED (GB) | 2021-05-20 | — | — | US | disclosed |
| US-20210079045-A1 | BICYCLIC PEPTIDE LIGANDS WITH DETECTABLE MOIETIES AND USES THEREOF | Bicyclerd Limited (GB) | 2021-03-18 | — | — | US | disclosed |
| US-9636643-B2 | Polymeric matrices formed from monomers comprising a protected amine group | GENERAL ELECTRIC COMPANY (US) | 2017-05-02 | — | — | US | disclosed |
| US-9636643-B2 | Polymeric matrices formed from monomers comprising a protected amine group | GENERAL ELECTRIC COMPANY (US) | 2017-05-02 | — | — | US | disclosed |
| US-9193678-B2 | Chemical agents capable of forming covalent 3-D networks | OXFORD ADVANCED SURFACES LTD (GB) | 2015-11-24 | — | — | US | disclosed |
| US-20140360932-A1 | POLYMERIC MATRICES FORMED FROM MONOMERS COMPRISING A PROTECTED AMINE GROUP | BL TECHNOLOGIES, INC. | 2014-12-11 | — | — | US | disclosed |
| US-8839960-B2 | Polymeric matrices formed from monomers comprising a protected amine group | GENERAL ELECTRIC COMPANY (US) | 2014-09-23 | — | — | US | disclosed |
| US-20120152839-A1 | MODIFIED SULFONAMIDE POLYMERIC MATRICES | BL TECHNOLOGIES, INC. | 2012-06-21 | — | — | US | disclosed |
| US-20120152822-A1 | POLYMERIC MATRICES FORMED FROM MONOMERS COMPRISING A PROTECTED AMINE GROUP | BL TECHNOLOGIES, INC. | 2012-06-21 | — | — | US | disclosed |
| US-20120021223-A1 | CHEMICAL AGENTS CAPABLE OF FORMING COVALENT 3-D NETWORKS | OXFORD ADVANCED SURFACES LTD. (GB) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11746126-B2 | Bicyclic peptide ligands with detectable moieties and uses thereof | VIP, NGLY1, GRPR | GAA 3314/4885KDM4E 4859/4885DBH 2282/4885 |
| US-20210147484-A1 | BICYCLIC PEPTIDE LIGANDS AND USES THEREOF | VIP, NGLY1, BID | GAA 3737/4885KDM4E 4848/4885DBH 2211/4885 |
| US-20210079045-A1 | BICYCLIC PEPTIDE LIGANDS WITH DETECTABLE MOIETIES AND USES THEREOF | VIP, NGLY1, GRPR | GAA 3314/4885KDM4E 4859/4885DBH 2282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.