Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS12 | P56730 | 11/20 | 0.51 |
| ▸ | F10 | P00742 | 5/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15283588 | 0.87 | PRSS12 (0.66) | PRSS12F10 | |
| SCHEMBL5540646 | 0.81 | PRSS12 (0.53) | PRSS12 | |
| SCHEMBL5539863 | 0.79 | MAPT (0.60) | PRSS12F10PIN1MAPTTP53 | |
| SCHEMBL15283224 | 0.77 | MAPT (0.60) | PRSS12F10PIN1MAPTTP53 | |
| SCHEMBL10246635 | 0.74 | PRSS12 (0.53) | PRSS12F10PIN1MAPT | |
| SCHEMBL15295600 | 0.73 | PRSS12 (0.68) | PRSS12 | |
| SCHEMBL5537970 | 0.73 | PRSS12 (0.56) | PRSS12MAPT | |
| SCHEMBL2734468 | 0.73 | PRSS12 (0.67) | PRSS12 | |
| SCHEMBL5539819 | 0.72 | PRSS12 (0.81) | PRSS12 | |
| SCHEMBL10246589 | 0.70 | PRSS12 (0.64) | PRSS12F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012059442-A2 | NEUROTRYPSIN INHIBITORS | NEUROTUNE AG (CH) | 2012-05-10 | — | — | WO | disclosed |