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Sugi Predict / Targets / PRSS12

PRSS12

Neurotrypsin · P56730 · PRSS12 on Sugi Atlas →

5,501 patent compounds predicted against PRSS12, 3,356 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL2732270 SCHEMBL2732270 1.00 20/20
SCHEMBL2722851 SCHEMBL2722851 0.81 20/20
SCHEMBL2733392 SCHEMBL2733392 0.80 20/20
SCHEMBL2721891 SCHEMBL2721891 0.77 20/20
SCHEMBL2732413 SCHEMBL2732413 0.68 20/20
SCHEMBL2734468 SCHEMBL2734468 0.67 20/20
SCHEMBL2722411 SCHEMBL2722411 0.86 19/20
SCHEMBL2724662 SCHEMBL2724662 0.85 19/20
SCHEMBL2724943 SCHEMBL2724943 0.73 19/20
SCHEMBL2723144 SCHEMBL2723144 0.69 19/20
SCHEMBL2733363 SCHEMBL2733363 0.69 19/20
SCHEMBL2724682 SCHEMBL2724682 0.82 17/20
SCHEMBL2733479 SCHEMBL2733479 1.00 16/20
SCHEMBL2724082 SCHEMBL2724082 0.83 16/20
SCHEMBL2724084 SCHEMBL2724084 0.83 16/20
SCHEMBL2722123 SCHEMBL2722123 0.72 16/20
SCHEMBL2733828 SCHEMBL2733828 0.63 16/20
SCHEMBL2732541 SCHEMBL2732541 0.68 15/20
SCHEMBL2724505 SCHEMBL2724505 0.64 15/20
SCHEMBL2733411 SCHEMBL2733411 1.00 14/20

Clinical trials — most relevant to PRSS12 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Improving Outcomes in Neonatal Abstinence Syndrome PHASE3COMPLETED
Neurosteroids for PTSD in Veterans PHASE2COMPLETED
Personalized Breast Cancer Screening nanACTIVE_NOT_RECRUITING
Parkinson's Foundation PD GENEration Genetic Registry nanRECRUITING
French National Cohort of Patients With PRSS1 Mutations nanRECRUITING
SNAP: Measurement of the Subjective Perception of the Symptom in Hereditary Spastic Paraparesis (HSP) nanCOMPLETED
Neurotrophin Expression in Infants as a Predictor of Respiratory and Neurodevelopmental Outcomes nanCOMPLETED
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Using Next-generation Sequencing in the Diagnosis of Epilepsy and/or Intellectual Disability in a Pediatric Cohorte nanCOMPLETED
Genetic Studies of Lysosomal Storage Disorders nanENROLLING_BY_INVITATION
The Man Van Project nanRECRUITING
Blood-based Biomarkers for the Prognosis of Sports Related Concussion nanCOMPLETED
Pharmacogenomic Response to Thyrotropin-Releasing Hormone Stimulation in Healthy Volunteers: The Influence of a Common Type 2 Deiodinase Genetic Polymorphism on Serum T3 nanCOMPLETED
Risk Factors for Progressive Supranuclear Palsy (PSP) nanCOMPLETED
Genetic Bases of Neuroendocrine Neoplasms in Mexican Patients nanRECRUITING
Progression Follow up of the First-degree Relatives of Patients With REM Sleep Behavior Disorder nanUNKNOWN
Genetics of Ehlers-Danlos Syndrome nanCOMPLETED
The Genetic Characterization of Dementia nanCOMPLETED
Genetics of Hypertension and Its Intermediate Phenotypes nanCOMPLETED
Performance of Inherited Risk Assessment for Predicting Prostate Cancer From Prostate Biopsy nanRECRUITING
Natural History Study of Smith-Magenis Syndrome nanACTIVE_NOT_RECRUITING
Genetic Basis of Abdominal Aortic Aneurysm nanCOMPLETED
Molecular Genetic Epidemiology of Endocardial Cushion Defects - SCOR in Pediatric Cardiovascular Disease nanCOMPLETED
Genome Environment Microbiome and Metabolome in Autism Study nanCOMPLETED
Circadian Rhythms and Sleep in Familial DSPS and ASPS nanCOMPLETED
Wolfram Syndrome and WFS1-related Disorders International Registry and Clinical Study nanRECRUITING
Down Syndrome Biomarker Initiative (DSBI) nanCOMPLETED
Genetic and Non-Genetic Breast Cancer Risk Prediction Evaluation in Indonesian Samples nanCOMPLETED
Family Blood Pressure Program - GENOA nanCOMPLETED
Molecular Epidemiology of Parkinson's Disease nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a PRSS12 binder may also engage these)

ProteinNameSimilarity
Q5G265 — 1.000 Q5G265 →
Q5G270 — 1.000 Q5G270 →
Q5G266 — 1.000 Q5G266 →
Q5G268 — 1.000 Q5G268 →
Q5G271 — 1.000 Q5G271 →
Q5G269 — 1.000 Q5G269 →
Q5G267 — 1.000 Q5G267 →
O08762 — 1.000 O08762 →
G3V801 — 1.000 G3V801 →
LOXL3 Lysyl oxidase homolog 3 0.995 landscape →
B4F6N6 — 0.995 B4F6N6 →
Q5R8J0 — 0.995 Q5R8J0 →
P11214 — 0.994 P11214 →
P19637 — 0.993 P19637 →
Q9Z175 — 0.993 Q9Z175 →
Q5RFQ6 — 0.992 Q5RFQ6 →
P04185 — 0.991 P04185 →
Q924C6 — 0.991 Q924C6 →
E1C3U7 — 0.991 E1C3U7 →
P49150 — 0.991 P49150 →
P85521 — 0.990 P85521 →
B8A4W9 — 0.990 B8A4W9 →
F1RD85 — 0.990 F1RD85 →
LOXL2 Lysyl oxidase homolog 2 0.990 landscape →
Q8SQ23 — 0.990 Q8SQ23 →
Q8MHY7 — 0.989 Q8MHY7 →
Q2VLH6 — 0.989 Q2VLH6 →
ST14 Suppressor of tumorigenicity 14 protein 0.989 landscape →
A6H737 — 0.989 A6H737 →
P29598 — 0.989 P29598 →