Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 11/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.44 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2772903 | 0.87 | S1PR1 (0.60) | S1PR1S1PR3 | |
| SCHEMBL10247088 | 0.84 | S1PR1 (0.44) | S1PR1S1PR3ENPP3ENPP1CD274 | |
| SCHEMBL408346 | 0.82 | S1PR1 (0.61) | S1PR1S1PR3 | |
| SCHEMBL2771358 | 0.80 | S1PR1 (0.51) | S1PR1S1PR3CD274HDAC6 | |
| SCHEMBL10247409 | 0.80 | S1PR1 (0.46) | S1PR1S1PR3ENPP3ENPP1CD274 | |
| SCHEMBL405590 | 0.80 | S1PR1 (0.58) | S1PR1S1PR3 | |
| SCHEMBL406842 | 0.80 | S1PR1 (0.53) | S1PR1S1PR3 | |
| SCHEMBL408025 | 0.79 | S1PR1 (0.51) | S1PR1S1PR3HDAC6 | |
| SCHEMBL408444 | 0.79 | S1PR1 (0.58) | S1PR1S1PR3 | |
| SCHEMBL406539 | 0.79 | S1PR1 (0.54) | S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120022109-A1 | OXADIAZOLE DERIVATIVES | MERCK SERONO SA (CH) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022109-A1 | OXADIAZOLE DERIVATIVES | OXA1L, HLA-DRB1, SSB | S1PR1 448/4885S1PR3 310/4885ENPP3 838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.