Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | GNRHR | P30968 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12205826 | 0.83 | TSHR (0.47) | TSHRLMNAHSD17B10ATMMEN1 | |
| SCHEMBL4790064 | 0.81 | MEN1 (0.42) | LMNAHSD17B10HTR2AHTR2CGNRHR | |
| SCHEMBL12724847 | 0.81 | TSHR (0.49) | TSHRLMNAHSD17B10ATMMEN1 | |
| SCHEMBL8130706 | 0.81 | CYP11B1 (0.45) | CYP11B1CYP11B2HTR2AHTR2CATM | |
| SCHEMBL13071405 | 0.80 | CYP11B1 (0.41) | CYP11B1CYP11B2HTR2AHTR2CKMT2A | |
| SCHEMBL3971362 | 0.80 | CYP11B1 (0.41) | CYP11B1CYP11B2HTR2AHTR2CMEN1 | |
| SCHEMBL1537613 | 0.80 | CYP11B1 (0.41) | CYP11B1CYP11B2HTR2AHTR2CMEN1 | |
| SCHEMBL10098954 | 0.75 | LMNA (0.66) | TSHRLMNAHSD17B10ATMMEN1 | |
| SCHEMBL12196521 | 0.75 | CCNT1 (0.55) | CYP11B1CYP11B2L3MBTL1 | |
| SCHEMBL11901564 | 0.74 | CYP11B1 (0.51) | TSHRLMNACYP11B1CYP11B2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093254-B2 | Aspartyl protease inhibitors | SCHERING CORPORATION (US) | 2012-01-10 | — | — | US | disclosed |
| US-20100069406-A1 | ASPARTYL PROTEASE INHIBITORS | SCHERING CORPORATION (US) | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069406-A1 | ASPARTYL PROTEASE INHIBITORS | BACE1, CHRM1, CHRM2 | TSHR 960/4885LMNA 2379/4885CYP11B1 913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.