Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8759222 | 0.79 | TAAR1 (0.50) | TAAR1ADRA2AADRA2BADRA2CCYP2A13 | |
| SCHEMBL7671113 | 0.77 | HSPA5 (0.48) | TAAR1TSHRMAPT | |
| SCHEMBL10249673 | 0.76 | TAAR1 (0.38) | TAAR1ADRA2AADRA2BADRA2CCYP2A13 | |
| SCHEMBL10249704 | 0.76 | TAAR1 (0.47) | TAAR1ADRA2AADRA2BADRA2CCYP2A13 | |
| SCHEMBL18372464 | 0.75 | IDO1 (0.50) | TAAR1ACHECHRM2KMT2AMAPT | |
| SCHEMBL13027232 | 0.74 | TAAR1 (0.43) | TAAR1ADRA2AADRA2BADRA2CCYP2A13 | |
| SCHEMBL17263571 | 0.74 | TAAR1 (0.39) | TAAR1ADRA2AADRA2BADRA2CCYP11B1 | |
| SCHEMBL5392773 | 0.74 | SLC6A4 (0.39) | NPC1RAB9A | |
| SCHEMBL1066724 | 0.73 | TAAR1 (0.46) | TAAR1CYP2A13CYP11B1CYP11B2TSHR | |
| SCHEMBL11652056 | 0.73 | TAAR1 (0.46) | TAAR1CYP2A13CYP11B1CYP11B2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9188887-B2 | Polycarbonate copolymer, coating fluid using same, electrophotographic photoreceptor, and method for producing polycarbonate copolymer | IDEMITSU KOSAN CO., LTD. (JP) | 2015-11-17 | — | — | US | disclosed |
| US-8519082-B2 | Polycarbonate copolymer, coating liquid using same, and electrophotographic photosensitive body | IDEMITSU KOSAN CO., LTD. (JP) | 2013-08-27 | — | — | US | disclosed |
| US-20120100474-A1 | POLYCARBONATE COPOLYMER, COATING LIQUID USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY | IDEMITSU KOSAN CO., LTD. (JP) | 2012-04-26 | — | — | US | disclosed |