Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | CASP1 | P29466 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.47 |
| ▸ | PRNP | P04156 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14946515 | 0.83 | KDM4E (0.76) | KDM4EALDH1A1HPGDGAACASP1 | |
| SCHEMBL18716583 | 0.81 | HPGD (0.44) | KDM4EALDH1A1HPGDGAACASP1 | |
| SCHEMBL17278339 | 0.76 | KDM4E (0.48) | KDM4EALDH1A1HPGDGAACASP1 | |
| SCHEMBL463202 | 0.75 | POLB (0.51) | KDM4EALDH1A1HPGDGAAKMT2A | |
| SCHEMBL17267938 | 0.73 | USP2 (0.43) | KDM4EALDH1A1HPGDGAAMEN1 | |
| SCHEMBL11894813 | 0.73 | KDM4E (0.56) | KDM4EALDH1A1HPGDGAACASP1 | |
| SCHEMBL30064775 | 0.71 | KDM4E (0.74) | KDM4EALDH1A1HPGDGAACASP1 | |
| SCHEMBL4461418 | 0.71 | KDM4E (0.74) | KDM4EALDH1A1HPGDGAACASP1 | |
| SCHEMBL16435362 | 0.70 | HCRTR2 (0.63) | KDM4EALDH1A1HPGDGAACASP1 | |
| SCHEMBL10255798 | 0.69 | KDM4E (0.69) | KDM4EALDH1A1HPGDGAACASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10334851-B2 | Herbicidal isoxazolo[5,4-B]pyridines | BASF SE (DE) | 2019-07-02 | — | — | US | disclosed |
| US-20170367340-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | BASF SE (DE) | 2017-12-28 | — | — | US | disclosed |
| US-9609870-B2 | Herbicidal isoxazolo[5,4-b]pyridines | BASF SE (DE) | 2017-04-04 | — | — | US | disclosed |
| US-9609870-B2 | Herbicidal isoxazolo[5,4-b]pyridines | BASF SE (DE) | 2017-04-04 | — | — | US | disclosed |
| US-20160037777-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | BASF SE (DE) | 2016-02-11 | — | — | US | disclosed |
| US-20160037777-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | BASF SE (DE) | 2016-02-11 | — | — | US | disclosed |
| US-9131695-B2 | Herbicidal isoxazolo[5,4-B]pyridines | BASF SE (DE) | 2015-09-15 | — | — | US | disclosed |
| US-9131695-B2 | Herbicidal isoxazolo[5,4-B]pyridines | BASF SE (DE) | 2015-09-15 | — | — | US | disclosed |
| US-20130123105-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | BASF SE (DE) | 2013-05-16 | — | — | US | disclosed |
| US-20130123105-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | BASF SE (DE) | 2013-05-16 | — | — | US | disclosed |
| WO-2012010633-A1 | HERBICIDAL ISOXAZOLO[5,4-B]PYRIDINES | BASF SE (DE) | 2012-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10334851-B2 | Herbicidal isoxazolo[5,4-B]pyridines | CYP4X1, PNPO, PRDX4 | KDM4E 972/4885ALDH1A1 292/4885HPGD 564/4885 |
| US-20130123105-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | CYP4X1, PNPO, PRDX4 | KDM4E 972/4885ALDH1A1 292/4885HPGD 564/4885 |
| US-20160037777-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | CYP4X1, PNPO, PRDX4 | KDM4E 972/4885ALDH1A1 292/4885HPGD 564/4885 |
| US-20170367340-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | CYP4X1, PNPO, PRDX4 | KDM4E 972/4885ALDH1A1 292/4885HPGD 564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.