PRDX4 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to PRDX4 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Role of Vitamin E in Gaucher Disease Patients	PHASE3	COMPLETED
Effect of Pioglitazone Administered to Patients With Friedreich's Ataxia: Proof of Concept	PHASE3	COMPLETED
Cardioprotective Effects of Melatonin in Patients With Cardiomyopathy	PHASE3	RECRUITING
Cysteine Supplementation in Critically Ill Neonates	PHASE2/PHASE3	UNKNOWN
Effect of Montelukast Versus Co Enzyme in Sepsis	PHASE2/PHASE3	COMPLETED
Beneficial Effect of Silymarin in Ulcerative Colitis	PHASE2	RECRUITING
N-Acetylcysteine for Neuroprotection in Parkinson's Disease	PHASE1/PHASE2	COMPLETED
Testing the Combination of MLN4924 (Pevonedistat), Carboplatin, and Paclitaxel in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) Who Have Previously Been Treated With Immunotherapy	PHASE2	ACTIVE_NOT_RECRUITING
A Supervised Nutritional Program in Pregnancies and NF-κB Expression in Placenta	PHASE1	COMPLETED
Electrophilic Fatty Acid Derivatives in Asthma	PHASE1	COMPLETED
Islet Isolation Using MnTE-2-PyP (BMX-010) - Pilot Study	PHASE1	COMPLETED
Antioxidant Signature in Adult Patients With Phenylketonuria	nan	COMPLETED
IVF Outcome in Polycystic Ovary Syndrome Patients	nan	UNKNOWN
Thiol/Disulphide Homeostasis in Unexplained Infertility	nan	COMPLETED
Cell Signaling and Resistance to Oxidative Stress: Effects of Aging and Exercise	nan	COMPLETED
Identification of Serum Level of Glutathione Peroxidase 4	nan	NOT_YET_RECRUITING
Investigating the Genetic Basis of Pseudoexfoliation Syndrome, Angle-closure Glaucoma and Primary Open-angle Glaucoma	nan	RECRUITING
Role of Nox2 in CNI-induced Renal Fibrosis	nan	COMPLETED
The Influence of Melatonin Supplementation in the Group of Persons Performing Competitive Sport.	nan	COMPLETED
Effect of Protein on Endoplasmic Reticulum Stress	nan	NOT_YET_RECRUITING
Chocolate and Physical Exercise to Reduce Malnutrition in Pre-dementia Aged People	nan	UNKNOWN
Evaluation of Mitochondrial Enzyme Activity in Cesarean Section Patients	nan	UNKNOWN
Role of USP35 in the Detection of Ferroptosis in Juvenile Autoimmune Hepatitis	nan	NOT_YET_RECRUITING
Targeting Oxidative Stress to Prevent Vascular and Skeletal Muscle Dysfunction During Disuse	nan	ACTIVE_NOT_RECRUITING
Protecting Autologous Free Flaps From Ischemia/Reperfusion Damage With Cold Storage.	nan	NOT_YET_RECRUITING
Effect of Sulfur Amino Acid Depletion and Acetaminophen on Plasma Glutatione	nan	COMPLETED
Comparison of Phoenixin-14 Levels in Term Babies	nan	COMPLETED
Molecular Hydrogen Inhalation: Effects on Health, Exercise Capacity and Inflammatory Response - in Vivo/in Vitro Studies	nan	NOT_YET_RECRUITING
Evaluation of the Predictive Effect of Inflammatory Markers in MI Patients	nan	UNKNOWN
The Effect of Aerobic and Anaerobic Exercise on Oxidative Stress and Cellular Fitness in Healthy Trained Young Men	nan	ENROLLING_BY_INVITATION

Related proteins — ESM-2 sequence neighbours (a PRDX4 binder may also engage these)

Protein	Name	Similarity
Q9BGI2	—	1.000	Q9BGI2 →
Q9Z0V5	—	0.995	Q9Z0V5 →
O08807	—	0.995	O08807 →
P35705	—	0.986	P35705 →
Q5REY3	—	0.986	Q5REY3 →
PRDX3	Thioredoxin-dependent peroxide reductase, mitochondrial	0.985	landscape →
Q2QEI3	—	0.985	Q2QEI3 →
Q9Z0V6	—	0.985	Q9Z0V6 →
P20108	—	0.983	P20108 →
Q5I3B2	—	0.983	Q5I3B2 →
AS3MT	Arsenite methyltransferase	0.982	landscape →
A6UPH7	—	0.982	A6UPH7 →
O42411	—	0.982	O42411 →
Q95N00	—	0.982	Q95N00 →
Q7XPE8	—	0.981	Q7XPE8 →
Q9HKX0	—	0.981	Q9HKX0 →
Q8VHT6	—	0.981	Q8VHT6 →
Q8RXN5	—	0.981	Q8RXN5 →
Q9CAE3	—	0.981	Q9CAE3 →
Q925S8	—	0.981	Q925S8 →
Q6L240	—	0.981	Q6L240 →
C4JF81	—	0.981	C4JF81 →
P70551	—	0.981	P70551 →
P27472	—	0.981	P27472 →
A0A061AE05	—	0.980	A0A061AE05 →
Q8TGA1	—	0.980	Q8TGA1 →
Q8MJ26	—	0.980	Q8MJ26 →
Q6LY19	—	0.980	Q6LY19 →
P55241	—	0.980	P55241 →
A2RRU1	—	0.980	A2RRU1 →