Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 6/20 | 0.42 |
| ▸ | ACE | P12821 | 5/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 2/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.39 |
| ▸ | ECE1 | P42892 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17509396 | 0.82 | ANPEP (0.36) | MMP2 | |
| SCHEMBL9068541 | 0.72 | MME (0.70) | MMEACECPA1ACE2NPSR1 | |
| SCHEMBL7379335 | 0.72 | MME (0.70) | MMEACECPA1ACE2NPSR1 | |
| SCHEMBL3580126 | 0.71 | MME (0.54) | MMEACECPA1ACE2NPSR1 | |
| SCHEMBL4087621 | 0.71 | MME (0.54) | MMEFPR2NPSR1NAALAD2MMP2 | |
| SCHEMBL10727371 | 0.71 | MME (0.61) | MMEACECPA1ACE2NPSR1 | |
| SCHEMBL28782920 | 0.70 | CSNK1E (0.52) | MMEMMP2 | |
| SCHEMBL27693401 | 0.70 | MME (0.60) | MMEACECPA1ACE2ECE1 | |
| Dl-Phenylalanine SCHEMBL28137250 | 0.69 | SLC7A5 (0.59) | MMP2 | |
| Diphenylmethane SCHEMBL28176599 | 0.69 | MIF (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008157228-A1 | NEW METHODS FOR TASTE-MASKING | CAMBREX CHARLES CITY, INC. (US) | 2008-12-24 | — | — | WO | claimed |
| EP-3538559-A1 | RECOMBINANT PMHC CLASS II MOLECULES | UTI Limited Partnership (CA) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018087597-A1 | RECOMBINANT PMHC CLASS II MOLECULES | UTI LIMITED PARTNERSHIP (CA) | 2018-05-17 | — | — | WO | disclosed |
| EP-2274619-A2 | MUCOSAL MEMBRANE RECEPTOR AND USES THEREOF | Universiteit Gent (BE) | 2011-01-19 | — | — | EP | disclosed |
| EP-2182943-A2 | METHODS AND COMPOSITIONS FOR TREATING FIBROSIS RELATED DISORDERS USING IL-17 ANTAGONISTS | Centocor Ortho Biotech Inc. (US) | 2010-05-12 | — | — | EP | disclosed |
| EP-2170387-A2 | ANTI- MCP-1 ANTIBODIES, COMPOSITIONS, METHODS AND USES | Centocor Ortho Biotech Inc. (US) | 2010-04-07 | — | — | EP | disclosed |
| WO-2009103555-A2 | MUCOSAL MEMBRANE RECEPTOR AND USES THEREOF | UNIVERSITEIT GENT (BE) | 2009-08-27 | — | — | WO | disclosed |
| WO-2009015063-A2 | METHODS AND COMPOSITIONS FOR TREATING FIBROSIS RELATED DISORDERS USING IL-17 ANTAGONISTS | CENTOCOR (US) | 2009-01-29 | — | — | WO | disclosed |
| WO-2009006359-A2 | ANTI- MCP-1 ANTIBODIES, COMPOSITIONS, METHODS AND USES | CENTOCOR, INC. (US) | 2009-01-08 | — | — | WO | disclosed |