SCHEMBL1025320

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1024049	0.89	PIK3CB (0.58)	PIK3CBPIK3CAHSD17B10TSHRALDH1A1
	SCHEMBL1023498	0.88	PIK3CB (0.61)	PIK3CBPIK3CAHSD17B10TSHRALDH1A1
	SCHEMBL4544429	0.86	PIK3CB (0.56)	PIK3CBPIK3CAHSD17B10TSHRALDH1A1
	SCHEMBL1024746	0.82	NPC1 (0.63)	PIK3CBPIK3CAHSD17B10TSHRALDH1A1
	SCHEMBL1024010	0.79	ESR1 (0.44)	PIK3CBPIK3CAHSD17B10TSHRALDH1A1
	SCHEMBL1026246	0.77	PIK3CB (0.50)	PIK3CBPIK3CAHSD17B10TSHRALDH1A1
	SCHEMBL1026248	0.76	PIK3CB (0.57)	PIK3CBPIK3CAHSD17B10TSHRALDH1A1
	SCHEMBL1023886	0.76	HSD17B10 (0.72)	PIK3CBPIK3CAHSD17B10TSHRALDH1A1
	SCHEMBL24295059	0.75	SMN1; SMN2 (0.57)	HSD17B10TSHRALDH1A1KDM4ESMN1; SMN2
	SCHEMBL14840780	0.75	FFAR1 (0.44)	AAK1ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.