Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 7/20 | 0.42 |
| ▸ | AHCY | P23526 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 3/20 | 0.33 |
| ▸ | PTPRC | P08575 | 2/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1026887 | 0.95 | ACKR3 (0.42) | ACKR3AHCYNAMPTPTPRCPRMT5 | |
| SCHEMBL1027342 | 0.93 | ACKR3 (0.43) | ACKR3AHCYNAMPTHDAC1HDAC3 | |
| SCHEMBL1029738 | 0.91 | AHCY (0.36) | ACKR3AHCYNAMPTHDAC1HDAC3 | |
| SCHEMBL1027669 | 0.90 | ACKR3 (0.46) | ACKR3AHCYNAMPTLMNAKDM4E | |
| SCHEMBL1026070 | 0.88 | ACKR3 (0.42) | ACKR3AHCYNAMPTHDAC1HDAC3 | |
| SCHEMBL1025935 | 0.88 | ACKR3 (0.48) | ACKR3AHCYMETAP2 | |
| SCHEMBL1027778 | 0.87 | ACKR3 (0.43) | ACKR3AHCYHDAC1METAP2 | |
| SCHEMBL1027490 | 0.86 | ACKR3 (0.43) | ACKR3AHCYMETAP2 | |
| SCHEMBL1026545 | 0.86 | AHCY (0.36) | ACKR3AHCYNAMPTHDAC1HDAC3 | |
| SCHEMBL1029781 | 0.85 | ACKR3 (0.44) | ACKR3AHCYNAMPTHDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486925-A1 | THERAPEUTIC AGENT FOR CEREBRAL INFARCTION | Mitsubishi Tanabe Pharma Corporation (JP) | 2012-08-15 | — | — | EP | disclosed |
| EP-2275404-A1 | HOMOCYSTEINE SYNTHASE INHIBITOR | Mitsubishi Tanabe Pharma Corporation (JP) | 2011-01-19 | — | — | EP | disclosed |