Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12260909 | 0.87 | MAOB (0.49) | MAOBMAOAAPPACHE | |
| SCHEMBL27113169 | 0.86 | MRGPRX4 (0.52) | MAOBMAOAPARP10NPC1RAB9A | |
| SCHEMBL257785 | 0.85 | MRGPRX4 (0.58) | MAOBMAOAAPPACHE | |
| SCHEMBL13929699 | 0.84 | MAOB (0.53) | MAOBMAOAPARP10NPC1RAB9A | |
| SCHEMBL258025 | 0.83 | MAOB (0.49) | MAOBMAOAAPP | |
| SCHEMBL12260744 | 0.81 | MRGPRX4 (0.45) | MAOBMAOAAPPACHE | |
| SCHEMBL2556050 | 0.81 | MAOB (0.54) | MAOBMAOAPARP10NPC1RAB9A | |
| SCHEMBL257777 | 0.80 | MRGPRX4 (0.57) | DRD4TMEM97SIGMAR1 | |
| SCHEMBL17548012 | 0.79 | MRGPRX4 (0.56) | MAOBMAOAPARP10NPC1RAB9A | |
| SCHEMBL891195 | 0.79 | MAOB (0.69) | MAOBMAOAPARP10NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2404607-A1 | Boronic acids and esters as inhibitors of fatty acid amide hydrolase | Infinity Pharmaceuticals, Inc. (US) | 2012-01-11 | — | — | EP | disclosed |