Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 7/20 | 0.57 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.43 |
| ▸ | DRD4 | P21917 | 3/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26434787 | 0.86 | MRGPRX4 (0.58) | MRGPRX4FFAR4LMNAHTTPTGER1 | |
| SCHEMBL12260905 | 0.84 | MRGPRX4 (0.42) | MRGPRX4FFAR4DRD4TMEM97SIGMAR1 | |
| SCHEMBL15588794 | 0.83 | MRGPRX4 (0.56) | MRGPRX4FFAR4LMNAHTTFFAR1 | |
| SCHEMBL10269467 | 0.81 | ENPP2 (0.44) | MRGPRX4FFAR4DRD4TMEM97SIGMAR1 | |
| SCHEMBL16210864 | 0.81 | MRGPRX4 (0.53) | MRGPRX4LMNAHTT | |
| SCHEMBL171841 | 0.80 | MRGPRX4 (0.68) | MRGPRX4FFAR4HTTPTGER1 | |
| SCHEMBL10269419 | 0.80 | MAOB (0.51) | DRD4TMEM97SIGMAR1 | |
| SCHEMBL26698908 | 0.80 | MRGPRX4 (0.56) | MRGPRX4FFAR4RXRARXRBRXRG | |
| SCHEMBL23624640 | 0.78 | MRGPRX4 (0.45) | MRGPRX4FFAR4PPARAFFAR1 | |
| SCHEMBL16210297 | 0.77 | MRGPRX4 (0.53) | MRGPRX4FFAR4LMNAHTTPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2399585-A1 | Boronic acids and esters as inhibitors of fatty acid amide hydrolase | Infinity Pharmaceuticals, Inc. (US) | 2011-12-28 | — | — | EP | disclosed |