SCHEMBL10270106

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL572471	1.00	NSD2 (0.44)	NSD2EHMT2HPGDHRH2HRH1
	SCHEMBL572184	0.94	NSD2 (0.49)	NSD2EHMT2HPGDMEN1KMT2A
	SCHEMBL573186	0.90	NSD2 (0.39)	NSD2EHMT2HPGDHRH2HRH1
	SCHEMBL572235	0.90	NSD2 (0.39)	NSD2EHMT2HPGDHRH2HRH1
	SCHEMBL573185	0.90	NSD2 (0.39)	NSD2EHMT2HPGDHRH2HRH1
	SCHEMBL573840	0.88	NSD2 (0.46)	NSD2EHMT2HPGDHRH2HRH1
	SCHEMBL10270888	0.85	KDM4E (0.43)	EHMT2MEN1KMT2AKDM4EALDH1A1
	SCHEMBL572765	0.85	KDM4E (0.43)	EHMT2MEN1KMT2AKDM4EALDH1A1
	SCHEMBL571665	0.85	KDM4E (0.45)	MEN1KMT2AKDM4EALDH1A1LMNA
	SCHEMBL572585	0.84	KDM4E (0.42)	MEN1KMT2AKDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.