Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 12/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.39 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL106273 | 0.96 | MAPT (0.46) | RORCMAPTGPR119PDK2ENPP2 | |
| SCHEMBL106274 | 0.96 | MAPT (0.46) | RORCMAPTGPR119PDK2ENPP2 | |
| SCHEMBL104144 | 0.87 | RORC (0.46) | RORCGPR119SMARCA2SMARCA4PBRM1 | |
| SCHEMBL104145 | 0.87 | RORC (0.46) | RORCGPR119SMARCA2SMARCA4PBRM1 | |
| SCHEMBL104146 | 0.87 | RORC (0.46) | RORCGPR119SMARCA2SMARCA4PBRM1 | |
| SCHEMBL103326 | 0.87 | RORC (0.46) | RORCGPR119SMARCA2SMARCA4PBRM1 | |
| SCHEMBL102624 | 0.87 | RORC (0.41) | RORC | |
| SCHEMBL102623 | 0.87 | RORC (0.41) | RORC | |
| SCHEMBL168097 | 0.81 | SLC2A1 (0.44) | RORCGPR119PDK2SMARCA2SMARCA4 | |
| SCHEMBL168096 | 0.81 | SLC2A1 (0.44) | RORCGPR119PDK2SMARCA2SMARCA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426113-A1 | CARBINOL COMPOUND HAVING HETEROCYCLIC LINKER | Kowa Company, Ltd. (JP) | 2012-03-07 | — | — | EP | disclosed |