Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 9/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13309114 | 0.86 | CREBBP (0.48) | SLC6A2SLC6A3MAPTBRD4CREBBP | |
| SCHEMBL10270321 | 0.80 | TSHR (0.41) | SLC6A2SLC6A3SLC6A4MAPTHTT | |
| SCHEMBL27473680 | 0.73 | MEN1 (0.55) | MAPTHTTNPSR1TSHRGFER | |
| SCHEMBL27473696 | 0.73 | MEN1 (0.55) | MAPTHTTNPSR1TSHRGFER | |
| SCHEMBL27476976 | 0.73 | MEN1 (0.55) | MAPTHTTNPSR1TSHRGFER | |
| SCHEMBL30499386 | 0.73 | MEN1 (0.55) | MAPTHTTNPSR1TSHRGFER | |
| SCHEMBL27473433 | 0.73 | MEN1 (0.55) | MAPTHTTNPSR1TSHRGFER | |
| SCHEMBL9384154 | 0.73 | MEN1 (0.55) | MAPTHTTNPSR1TSHRGFER | |
| SCHEMBL3458514 | 0.70 | MAPT (0.43) | MAPTHTTNPSR1TSHRGFER | |
| SCHEMBL3458510 | 0.70 | CREBBP (0.44) | MAPTHTTNPSR1TSHRGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415764-A1 | PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR ANEMIA COMPRISING TETRAHYDROQUINOLINE COMPOUND AS ACTIVE INGREDIENT | Kowa Company, Ltd. (JP) | 2012-02-08 | — | — | EP | disclosed |