Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NQO2 | P16083 | 1/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 6/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 6/20 | 0.51 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | HPGDS | O60760 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10272593 | 0.93 | ALDH1A1 (0.51) | ALDH1A1MEN1POLBRAB9AKMT2A | |
| SCHEMBL29234078 | 0.79 | PDGFRB (0.50) | ALDH1A1MEN1POLBRAB9AKMT2A | |
| SCHEMBL10271472 | 0.77 | NQO2 (0.47) | ALDH1A1MEN1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL12844007 | 0.77 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2KDM4ENQO2PDGFRB | |
| SCHEMBL14970152 | 0.77 | ALDH1A1 (0.56) | ALDH1A1MEN1POLBRAB9AKMT2A | |
| SCHEMBL23651807 | 0.76 | ALDH1A1 (0.55) | ALDH1A1MEN1POLBRAB9AKMT2A | |
| SCHEMBL17179175 | 0.76 | FGFR3 (0.47) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL559347 | 0.76 | ALDH1A1 (0.55) | ALDH1A1MEN1POLBRAB9AKMT2A | |
| SCHEMBL621383 | 0.76 | ALDH1A1 (0.55) | ALDH1A1MEN1POLBRAB9AKMT2A | |
| SCHEMBL17179171 | 0.76 | HTT (0.41) | ALDH1A1MEN1KMT2AHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120035189-A1 | Quinuclidine Compounds as Alpha-7 Nicotinic Acetylcholine Receptor Ligands | BRISTOL-MYERS SQUIBB COMPANY | 2012-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035189-A1 | Quinuclidine Compounds as Alpha-7 Nicotinic Acetylcholine Receptor Ligands | CHRNA7, CHRNA5, CHRNA6 | ALDH1A1 1082/4885MEN1 3838/4885POLB 2083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.