Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10273213 | 0.91 | LMNA (0.39) | SMN1; SMN2NPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL10272867 | 0.89 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL10273211 | 0.87 | LMNA (0.40) | SMN1; SMN2NPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL16172553 | 0.87 | LMNA (0.36) | SMN1; SMN2NPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL10272862 | 0.84 | LMNA (0.38) | SMN1; SMN2NPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL10273210 | 0.83 | TBXA2R (0.44) | SMN1; SMN2NPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL10272861 | 0.82 | TBXA2R (0.42) | SMN1; SMN2NPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL16172555 | 0.82 | TBXA2R (0.42) | SMN1; SMN2NPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL16172520 | 0.81 | KCNH2 (0.35) | SMN1; SMN2NPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL10273812 | 0.80 | KCNH2 (0.40) | SMN1; SMN2NPC1RAB9ALMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038521-A1 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-03-29 | — | — | WO | disclosed |