Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 16/20 | 0.46 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3802034 | 0.93 | SRD5A1 (0.53) | CYP19A1SRD5A1 | |
| SCHEMBL10274355 | 0.84 | CYP19A1 (0.66) | CYP19A1 | |
| SCHEMBL10273335 | 0.79 | CYP19A1 (0.69) | CYP19A1SRD5A1 | |
| SCHEMBL10274353 | 0.76 | SRD5A1 (0.51) | CYP19A1SRD5A1 | |
| SCHEMBL5183889 | 0.76 | SRD5A1 (0.53) | CYP19A1SRD5A1 | |
| SCHEMBL5183886 | 0.76 | SRD5A1 (0.53) | CYP19A1SRD5A1 | |
| SCHEMBL10274118 | 0.76 | CYP19A1 (0.65) | CYP19A1CYP1B1 | |
| SCHEMBL10273637 | 0.76 | CYP19A1 (0.65) | CYP19A1CYP1B1 | |
| SCHEMBL3797856 | 0.76 | CYP19A1 (0.58) | CYP19A1SRD5A1 | |
| SCHEMBL7529519 | 0.76 | CYP19A1 (0.58) | CYP19A1SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130252930-A1 | CYP11B, CYP17, AND/OR CYP21 INHIBITORS | BIOMARIN PHARMACEUTICAL INC. (CA) | 2013-09-26 | — | — | US | disclosed |
| US-20130252930-A1 | CYP11B, CYP17, AND/OR CYP21 INHIBITORS | BIOMARIN PHARMACEUTICAL INC. (CA) | 2013-09-26 | — | — | US | disclosed |
| WO-2012083112-A2 | CYP11B, CYP17, AND/OR CYP21 INHIBITORS | BIOMARIN PHARMACEUTICAL INC. (US) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130252930-A1 | CYP11B, CYP17, AND/OR CYP21 INHIBITORS | CYP4A11, HSD17B11, CYP21A2 | CYP19A1 10/4885SRD5A1 38/4885CYP1B1 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.