Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 3/20 | 0.37 |
| ▸ | HTR1B | P28222 | 3/20 | 0.37 |
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1027545 | 0.99 | LMNA (0.38) | LMNAMAPTHTR1DHTR1BHTR2A | |
| SCHEMBL1027188 | 0.91 | MAPT (0.38) | LMNAMAPTHTR1DHTR1BHTR2A | |
| SCHEMBL1024361 | 0.91 | MAPK14 (0.37) | LMNAHTR1DHTR1BHTR2AMAPK14 | |
| Hydrochloric Acid SCHEMBL1024154 | 0.91 | MAPT (0.38) | LMNAMAPTHTR1DHTR1BHTR2A | |
| SCHEMBL1027365 | 0.91 | LMNA (0.35) | LMNAHTR1DHTR1BHTR2ATHRB | |
| Hydrochloric Acid SCHEMBL1027402 | 0.90 | MAPK14 (0.36) | LMNAHTR1DHTR1BHTR2AMAPK14 | |
| Hydrochloric Acid SCHEMBL1026435 | 0.90 | LMNA (0.35) | LMNAHTR1DHTR1BHTR2ATHRB | |
| Hydrochloric Acid SCHEMBL1025409 | 0.88 | KIT (0.35) | LMNAMAPTHTR1DHTR1BHTR2A | |
| SCHEMBL1028852 | 0.88 | MAPT (0.38) | LMNAMAPTHTR1DHTR1BHTR2A | |
| Hydrochloric Acid SCHEMBL1027389 | 0.87 | HTR1D (0.37) | LMNAMAPTHTR1DHTR1BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2275404-A1 | HOMOCYSTEINE SYNTHASE INHIBITOR | Mitsubishi Tanabe Pharma Corporation (JP) | 2011-01-19 | — | — | EP | disclosed |