Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12607856 | 0.94 | CTSK (0.57) | CTSK | |
| SCHEMBL18381504 | 0.82 | CTSK (0.62) | CTSK | |
| SCHEMBL31471965 | 0.82 | CTSK (0.71) | CTSK | |
| SCHEMBL6121843 | 0.82 | CTSK (0.60) | CTSK | |
| SCHEMBL18190180 | 0.82 | CTSK (0.60) | CTSK | |
| SCHEMBL2401647 | 0.81 | CTSK (0.61) | CTSK | |
| SCHEMBL10766560 | 0.81 | CTSK (0.61) | CTSK | |
| SCHEMBL8404696 | 0.81 | CTSK (0.50) | CTSK | |
| SCHEMBL3623912 | 0.81 | CTSK (0.78) | CTSK | |
| SCHEMBL8576225 | 0.81 | CTSK (0.78) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013074386-A2 | HCV NS3 PROTEASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2013-05-23 | — | — | WO | disclosed |
| WO-2012040242-A1 | SUBSTITUTED PROLINE INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2012-03-29 | — | — | WO | disclosed |