Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 4/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL765446 | 0.91 | POLB (0.34) | BTKEPHX1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22042675 | 0.91 | POLB (0.34) | BTKEPHX1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5433248 | 0.89 | EPHX1 (0.44) | BTKEPHX1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5433253 | 0.89 | EPHX1 (0.44) | BTKEPHX1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5433245 | 0.89 | EPHX1 (0.44) | BTKEPHX1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17504487 | 0.89 | EPHX1 (0.44) | BTKEPHX1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14922428 | 0.83 | ALDH1A1 (0.53) | BTKEPHX1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18502884 | 0.83 | ALDH1A1 (0.53) | BTKEPHX1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15970269 | 0.82 | ATM (0.34) | KDM4EALDH1A1 | |
| SCHEMBL15970268 | 0.82 | ATM (0.34) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1439174-B1 | 4-IMIDAZOLIN-2-ONE COMPOUNDS AS p38 MAP KINASE INHIBITORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2012-03-21 | — | — | EP | disclosed |