Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 15/20 | 0.43 |
| ▸ | CDK6 | Q00534 | 7/20 | 0.43 |
| ▸ | CDK1 | P06493 | 3/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.43 |
| ▸ | CCND1 | P24385 | 3/20 | 0.43 |
| ▸ | CCND3 | P30281 | 2/20 | 0.43 |
| ▸ | FLT3 | P36888 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL803946 | 0.82 | KDM4E (0.51) | PHGDHHRH3 | |
| SCHEMBL803705 | 0.81 | F10 (0.43) | PHGDH | |
| SCHEMBL803945 | 0.79 | PDE10A (0.44) | PHGDH | |
| SCHEMBL30738297 | 0.79 | CYP19A1 (0.54) | PHGDHCYP19A1MKNK2 | |
| SCHEMBL15516206 | 0.79 | CYP19A1 (0.54) | PHGDHCYP19A1MKNK2 | |
| SCHEMBL2362576 | 0.77 | CHKA (0.53) | FLT3HRH3KIT | |
| SCHEMBL6017418 | 0.75 | HTR3E (0.63) | PHGDHCYP19A1 | |
| SCHEMBL22837854 | 0.75 | NPY5R (0.53) | HRH3 | |
| Hydrochloric Acid SCHEMBL30609660 | 0.74 | HTR3E (0.61) | PHGDHCYP19A1 | |
| Hydrochloric Acid SCHEMBL2801289 | 0.74 | HTR3E (0.61) | PHGDHCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038081-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2012-03-29 | — | — | WO | disclosed |