Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16298158 | 1.00 | CTSB (0.52) | CTSBADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL10227219 | 1.00 | CTSB (0.52) | CTSBADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL10275452 | 0.96 | CTSB (0.52) | CTSBADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL10227214 | 0.96 | CTSB (0.52) | CTSBADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL10227175 | 0.91 | ADRB3 (0.59) | CTSBADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL10274816 | 0.91 | ADRB3 (0.59) | CTSBADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL14365688 | 0.89 | ADRB3 (0.52) | CTSBADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL10227216 | 0.88 | ADRB3 (0.52) | CTSBADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL10275623 | 0.88 | ADRB3 (0.52) | CTSBADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL10275969 | 0.87 | ADRB3 (0.58) | CTSBADRB3ADRA2BADRA2CCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442695-B2 | Depeptidized inhibitors of hepatitis C virus NS3 protease | SCHERING CORPORATION (US) | 2008-10-28 | — | — | US | disclosed |
| US-20070258947-A1 | Depeptidized Inhibitors of Hepatitis C Virus NS3 Protease | SCHERING CORPORATION | 2007-11-08 | — | — | US | disclosed |
| US-7253160-B2 | Depeptidized inhibitors of hepatitis C virus NS3 protease | SCHERING CORPORATION (US) | 2007-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070258947-A1 | Depeptidized Inhibitors of Hepatitis C Virus NS3 Protease | DPP3, DPP7, DPP4 | CTSB 78/4885ADRB3 3738/4885ADRA2B 4407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.