SCHEMBL1027583

SCHEMBL1027583

C1=CC(Cc2ccccc2)c2ccccc21

nearest known ligand 0.74

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 3/20 0.74
SIGMAR1 Q99720 6/20 0.45
HTR2A P28223 1/20 0.39
HDAC3 O15379 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC7 Q8WUI4 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
HDAC9 Q9UKV0 1/20 0.36
HDAC5 Q9UQL6 1/20 0.36
SLC22A1 O15245 1/20 0.35
PRCP P42785 1/20 0.35
GBA1 P04062 1/20 0.33
LTB4R Q15722 1/20 0.33
LTB4R2 Q9NPC1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30733629 0.89 HTR6 (0.65) HTR6SIGMAR1HTR2AHDAC3HDAC1
SCHEMBL21274224 0.89 HTR6 (0.65) HTR6SIGMAR1HTR2AHDAC3HDAC1
SCHEMBL15970383 0.87 HTR6 (0.73) HTR6SIGMAR1HTR2AHDAC3HDAC1
Lithium SCHEMBL30733633 0.87 HTR6 (0.63) HTR6SIGMAR1HTR2AHDAC3HDAC1
SCHEMBL11235389 0.85 HTR6 (0.66) HTR6SIGMAR1HTR2AHDAC3HDAC1
SCHEMBL12458689 0.85 HTR6 (0.71) HTR6SIGMAR1HTR2AHDAC3HDAC1
SCHEMBL13263606 0.85 HTR6 (0.71) HTR6SIGMAR1HTR2AHDAC3HDAC1
Hydrochloric Acid SCHEMBL11233156 0.84 HTR6 (0.64) HTR6SIGMAR1HTR2AHDAC3HDAC1
SCHEMBL29895080 0.83 HTR6 (0.67) HTR6SIGMAR1HTR2AHDAC3HDAC1
SCHEMBL7759382 0.82 HTR6 (0.61) HTR6SIGMAR1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3385288-B1 POLYMERIZATION CATALYST COMPOSITION, AND METHOD FOR PRODUCING CONJUGATED DIENE POLYMER BRIDGESTONE CORP (JP) 2025-06-04 EP claimed
US-10875937-B2 Terminal-modified conjugated diene polymer, rubber composition and rubber article BRIDGESTONE CORPORATION (JP) 2020-12-29 US claimed
CN-109071685-B Terminal-modified conjugated diene polymer, rubber composition, and rubber article 株式会社普利司通 2020-12-01 CN claimed
EP-0993478-B2 OLEFIN POLYMERIZATION PROCESS BOREALIS TECH OY (FI) 2011-01-19 EP claimed
US-6921799-B1 Olefin polymerization process BOREALIS A/S (DK) 2005-07-26 US claimed
CN-1157427-C Polymerization method for olefrines �����ɷ� 2004-07-14 CN claimed
EP-0993478-B1 OLEFIN POLYMERIZATION PROCESS BOREALIS TECH OY (FI) 2004-04-07 EP claimed
CN-1260807-A Polymerization method for olefrines BOREALL AS (DK) 2000-07-19 CN claimed
EP-3792307-B1 VULCANIZED RUBBER COMPOSITION, TIRE TREAD AND TIRE BRIDGESTONE CORP (JP) 2025-12-10 EP disclosed
US-12479935-B2 Polymerization processes for the production of cis-1,4-polydienes BRIDGESTONE CORPORATION (JP) 2025-11-25 US disclosed
EP-3722339-B1 COPOLYMER, RUBBER COMPOSITION, RESIN COMPOSITION, TIRE AND RESIN PRODUCT BRIDGESTONE CORP (JP) 2025-07-30 EP disclosed
EP-3722337-B1 COPOLYMER, RUBBER COMPOSITION, RESIN COMPOSITION, TIRE AND RESIN PRODUCT BRIDGESTONE CORP (JP) 2025-07-30 EP disclosed
EP-3385288-B1 POLYMERIZATION CATALYST COMPOSITION, AND METHOD FOR PRODUCING CONJUGATED DIENE POLYMER BRIDGESTONE CORP (JP) 2025-06-04 EP disclosed
EP-3543262-B1 MULTI-COMPONENT COPOLYMER, RUBBER COMPOSITION, CROSSLINKED RUBBER COMPOSITION AND RUBBER PRODUCT BRIDGESTONE CORP (JP) 2025-02-26 EP disclosed
US-5886202-A HAVING UNUSUAL EFFECTIVENESS AS CATALYSTS FOR THE POLYMERIZATION OF OLEFINS WHEN CERTAIN SUBSTITUENTS ARE AT THE 3 POSITION OF THE INDENE; HIGHER-MOLECULAR-WEIGHT POLYOLEFINS CHEVRON PHILLIPS CHEMICAL COMPANY LP 1999-03-23 US disclosed
US-5670589-A COORDINATION POLYMERIZATION CATALYST PHILLIPS PETROLEUM COMPANY (US) 1997-09-23 US disclosed
CN-1131670-A Organoaluminoxy product, catalyst systems, preparation, and use PHILLIPS PETROLEUM CO (US) 1996-09-25 CN disclosed
EP-0726271-A1 Organoaluminoxy product, catalyst systems, preparation, and use PHILLIPS PETROLEUM COMPANY (US) 1996-08-14 EP disclosed
US-3970693-A Process for preparing indene acetic acids MERCK & CO., INC. (US) 1976-07-20 US disclosed
US-3944600-A Indenylidene-3-acetic acid process for preparing indene acetic acids MERCK & CO., INC. (US) 1976-03-16 US disclosed