Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 6/20 | 0.39 |
| ▸ | FNTB | P49356 | 6/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 5/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10275952 | 0.85 | FNTA (0.39) | FNTAFNTBPGGT1BKDM1AMAPK14 | |
| SCHEMBL10275293 | 0.82 | KDM1A (0.39) | FNTAFNTBPGGT1BKDM1AMAPK14 | |
| SCHEMBL10276206 | 0.80 | FNTA (0.36) | FNTAFNTBPGGT1BKDM1AMAPK14 | |
| SCHEMBL10275867 | 0.78 | PI4KB (0.41) | FNTAFNTBPGGT1BMAPK14 | |
| SCHEMBL10313872 | 0.78 | BRD4 (0.39) | FNTAFNTBPGGT1BMAPK14 | |
| SCHEMBL10275567 | 0.76 | CHEK1 (0.37) | FNTAFNTBPGGT1BKDM1APGR | |
| SCHEMBL10276290 | 0.76 | FNTA (0.34) | FNTAFNTBPGGT1BMAPK14PGR | |
| SCHEMBL10275521 | 0.76 | AR (0.36) | FNTAFNTBPGGT1BKDM1APGR | |
| SCHEMBL10282686 | 0.75 | FNTA (0.34) | FNTAFNTBPGGT1BMAPK14 | |
| SCHEMBL10276646 | 0.73 | FNTA (0.35) | FNTAFNTBPGGT1BMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120178915-A1 | PYRIMIDINE DERIVATIVES AND ANALOGS, PREPARATION METHOD AND USE THEREOF | XU LIFENG (US) | 2012-07-12 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178915-A1 | PYRIMIDINE DERIVATIVES AND ANALOGS, PREPARATION METHOD AND USE THEREOF | TYMP, TYMS, ADORA3 | FNTA 3998/4885FNTB 3608/4885PGGT1B 2260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.