SCHEMBL10276916

SCHEMBL10276916

O=C(O)CCCCCCCCCCc1ccc(Cl)cc1Cl

nearest known ligand 0.78

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ACLY P53396 8/20 0.65
NAAA Q02083 1/20 0.56
F13A1 P00488 3/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6207183 0.98 ACLY (0.63) ACLYNAAAF13A1
SCHEMBL4778926 0.95 ACLY (0.58) ACLY
Hydrochloric Acid SCHEMBL9083841 0.93 ACLY (0.57) ACLY
SCHEMBL11037069 0.87 ACLY (0.59) ACLYNAAA
SCHEMBL19612677 0.87 ACLY (0.58) ACLYNAAA
SCHEMBL20672330 0.87 F13A1 (0.56) ACLYNAAAF13A1
SCHEMBL586345 0.86 PDPK1 (0.59) ACLY
SCHEMBL30567601 0.86 PDPK1 (0.59) ACLY
SCHEMBL11041035 0.85 ACLY (0.56) ACLYNAAA
SCHEMBL11637870 0.85 ACLY (0.56) ACLYNAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10654880-B2 Methods for preparation of glycosphingolipids and uses thereof LIANG PI HUI (TW) 2020-05-19 US disclosed
US-10654880-B2 Methods for preparation of glycosphingolipids and uses thereof LIANG PI HUI (TW) 2020-05-19 US disclosed
EP-2661440-B1 METHOD FOR THE PREPARATION OF GLYCOSPHINGOLIPIDS UNIV NAT TAIWAN (TW) 2017-09-27 EP disclosed
EP-2661440-B1 METHOD FOR THE PREPARATION OF GLYCOSPHINGOLIPIDS UNIV NAT TAIWAN (TW) 2017-09-27 EP disclosed
US-20160229881-A1 METHODS FOR PREPARATION OF GLYCOSPHINGOLIPIDS AND USES THEREOF LIANG PI-HUI (TW) 2016-08-11 US disclosed
US-20160229881-A1 METHODS FOR PREPARATION OF GLYCOSPHINGOLIPIDS AND USES THEREOF LIANG PI-HUI (TW) 2016-08-11 US disclosed
US-20160229881-A1 METHODS FOR PREPARATION OF GLYCOSPHINGOLIPIDS AND USES THEREOF LIANG PI-HUI (TW) 2016-08-11 US disclosed
US-9181292-B2 Methods for preparation of glycosphingolipids and uses thereof LIANG PI-HUI (TW) 2015-11-10 US disclosed
US-9181292-B2 Methods for preparation of glycosphingolipids and uses thereof LIANG PI-HUI (TW) 2015-11-10 US disclosed
US-9181292-B2 Methods for preparation of glycosphingolipids and uses thereof LIANG PI-HUI (TW) 2015-11-10 US disclosed
EP-2661440-A2 METHODS FOR PREPARATION OF GLYCOSPHINGOLIPIDS AND USES THEREOF National Taiwan University (TW) 2013-11-13 EP disclosed
US-20120178705-A1 METHODS FOR PREPARATION OF GLYCOSPHINGOLIPIDS AND USES THEREOF NATIONAL TAIWAN UNIVERSITY (TW) 2012-07-12 US disclosed
US-20120178705-A1 METHODS FOR PREPARATION OF GLYCOSPHINGOLIPIDS AND USES THEREOF NATIONAL TAIWAN UNIVERSITY (TW) 2012-07-12 US disclosed
US-20120178705-A1 METHODS FOR PREPARATION OF GLYCOSPHINGOLIPIDS AND USES THEREOF NATIONAL TAIWAN UNIVERSITY (TW) 2012-07-12 US disclosed
WO-2012094540-A2 METHODS FOR PREPARATION OF GLYCOSPHINGOLIPIDS AND USES THEREOF NATIONAL TAIWAN UNIVERSITY (TW) 2012-07-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120178705-A1 METHODS FOR PREPARATION OF GLYCOSPHINGOLIPIDS AND USES THEREOF UGCG, CERS2, SGMS1 ACLY 1280/4885NAAA 548/4885F13A1 679/4885
US-20160229881-A1 METHODS FOR PREPARATION OF GLYCOSPHINGOLIPIDS AND USES THEREOF UGCG, CERS2, SGMS1 ACLY 1280/4885NAAA 548/4885F13A1 679/4885
US-10654880-B2 Methods for preparation of glycosphingolipids and uses thereof UGCG, CERS2, SGMS1 ACLY 1280/4885NAAA 548/4885F13A1 679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.