SCHEMBL10277587

SCHEMBL10277587

Cc1ccccc1C(=O)P(=O)(OC1CCCCC1F)OC1CCCCC1F

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.45
RAB9A P51151 1/20 0.45
TP53 P04637 1/20 0.37
HTT P42858 1/20 0.35
KMT2A Q03164 4/20 0.35
MEN1 O00255 2/20 0.35
TAS1R3 Q7RTX0 1/20 0.35
TAS1R1 Q7RTX1 1/20 0.35
TAS1R2 Q8TE23 1/20 0.35
GLA P06280 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HSD11B1 P28845 1/20 0.35
CXCR5 P32302 1/20 0.35
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4610702 0.82 NPC1 (0.50) NPC1RAB9ATP53HTTKMT2A
SCHEMBL776414 0.81 NPC1 (0.52) NPC1RAB9ATP53HTTKMT2A
SCHEMBL4612329 0.79 NPC1 (0.47) NPC1RAB9ATP53HTTKMT2A
SCHEMBL10277616 0.78 RAB9A (0.42) NPC1RAB9AKMT2AMEN1SMN1; SMN2
SCHEMBL812084 0.78 NPC1 (0.46) NPC1RAB9AHTTKMT2A
SCHEMBL777962 0.76 NPC1 (0.47) NPC1RAB9ATP53HTTKMT2A
SCHEMBL4132350 0.75 NPC1 (0.33) NPC1RAB9AKMT2AMEN1GLA
SCHEMBL779150 0.75 NPC1 (0.49) NPC1RAB9ATP53HTTKMT2A
SCHEMBL777088 0.70 NPC1 (0.47) NPC1RAB9ATP53HTTKMT2A
SCHEMBL776959 0.70 NPC1 (0.46) NPC1RAB9AHTTKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9343777-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-05-17 US disclosed
US-20120177988-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-07-12 US disclosed