SCHEMBL10277598

SCHEMBL10277598

Cc1ccccc1C(=O)P(=O)(Oc1ccccc1F)Oc1ccccc1F

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.49
GAA P10253 4/20 0.49
HTT P42858 3/20 0.49
MAPK1 P28482 1/20 0.49
SMN1; SMN2 Q16637 3/20 0.48
NPC1 O15118 3/20 0.48
KMT2A Q03164 6/20 0.46
MEN1 O00255 3/20 0.46
NPSR1 Q6W5P4 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
RAB9A P51151 3/20 0.43
POLB P06746 3/20 0.43
KAT6A Q92794 2/20 0.43
MAPT P10636 1/20 0.43
HSD17B10 Q99714 1/20 0.41
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4609809 0.81 KMT2A (0.45) GAAHTTMAPK1SMN1; SMN2NPC1
SCHEMBL779617 0.79 HPGD (0.46) LMNANPC1KMT2ACYP3A4CYP2C9
SCHEMBL10277660 0.78 LMNA (0.56) LMNAGAAHTTMAPK1SMN1; SMN2
SCHEMBL776959 0.76 NPC1 (0.46) LMNAHTTSMN1; SMN2NPC1KMT2A
SCHEMBL778118 0.76 CYP3A4 (0.47) LMNANPC1KMT2AMEN1NPSR1
SCHEMBL778117 0.74 HPGD (0.45) GAAHTTSMN1; SMN2NPC1KMT2A
SCHEMBL779208 0.73 KMT2A (0.46) LMNAGAAHTTSMN1; SMN2NPC1
SCHEMBL4124385 0.72 LMNA (0.52) LMNAGAAHTTMAPK1SMN1; SMN2
SCHEMBL779439 0.72 KMT2A (0.58) LMNAGAAHTTSMN1; SMN2NPC1
SCHEMBL4610754 0.72 HPGD (0.42) LMNAHTTSMN1; SMN2NPC1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9343777-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-05-17 US disclosed
US-20120177988-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-07-12 US disclosed