Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 3/20 | 0.32 |
| ▸ | PPARA | Q07869 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL361578 | 0.91 | PPARD (0.31) | MAOBPPARDPPARA | |
| SCHEMBL10356028 | 0.89 | PPARD (0.31) | PPARDPPARA | |
| SCHEMBL362670 | 0.87 | MAPT (0.31) | PPARDPPARAKMT2APIN1 | |
| SCHEMBL10356249 | 0.85 | MEN1 (0.36) | MAOBPPARDPPARAMEN1KMT2A | |
| SCHEMBL10279805 | 0.83 | UGT1A1 (0.38) | PPARDPPARA | |
| SCHEMBL10279544 | 0.83 | KDM4E (0.36) | MAOBMEN1KMT2AKDM4E | |
| SCHEMBL10356368 | 0.83 | PPARD (0.32) | PPARDPPARA | |
| SCHEMBL10353221 | 0.80 | PPARD (0.30) | PPARDPPARA | |
| SCHEMBL18023124 | 0.80 | — | — | |
| SCHEMBL362725 | 0.78 | PSEN1 (0.36) | MAOBPPARDPPARAGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009309-A1 | COMPOUNDS FOR THE REDUCTION OF BETA-AMYLOID PRODUCTION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-01-19 | — | — | WO | disclosed |