Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.34 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.30 |
| ▸ | TUBAL3 | A6NHL2 | 1/20 | 0.30 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.30 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.30 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.30 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.30 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.30 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.30 |
| ▸ | TUBA8 | Q9NY65 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15187037 | 0.83 | GRIK1 (0.33) | GRIK1GRIK2 | |
| SCHEMBL17518330 | 0.82 | — | — | |
| SCHEMBL13510737 | 0.82 | — | — | |
| SCHEMBL17087581 | 0.81 | GRIK1 (0.34) | GRIK1GRIK2 | |
| SCHEMBL17919993 | 0.80 | GRIK1 (0.30) | GRIK1GRIK2 | |
| SCHEMBL17920241 | 0.80 | GRIK1 (0.30) | GRIK1GRIK2 | |
| SCHEMBL13447538 | 0.80 | GRIK1 (0.39) | GRIK1GRIK2CTSK | |
| SCHEMBL19984497 | 0.80 | GRIK1 (0.39) | GRIK1GRIK2CTSK | |
| SCHEMBL18737070 | 0.79 | — | — | |
| SCHEMBL17518273 | 0.77 | CTSK (0.31) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012021796-A2 | NOVEL CYCLOSPORIN DERIVATIVES FOR THE TREATMENT AND PREVENTION OF A VIRAL INFECTION | S&T GLOBAL, INC. (US) | 2012-02-16 | — | — | WO | disclosed |