SCHEMBL1028107

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4544502	0.86	MAPT (0.47)	F2RL3HDAC6TSHRHSD17B10PDE10A
	SCHEMBL1024114	0.83	HSD17B10 (0.46)	F2RL3HDAC3HDAC1HDAC2HDAC8
	SCHEMBL1025865	0.83	AGPAT2 (0.47)	HDAC3HDAC1HDAC2HDAC8HDAC6
	SCHEMBL4544454	0.80	KDM4E (0.51)	TSHRHSD17B10MAPTKDM4EALDH1A1
	SCHEMBL1025231	0.79	F2RL3 (0.47)	F2RL3HDAC3HDAC1HDAC2HDAC8
	SCHEMBL1023886	0.77	HSD17B10 (0.72)	F2RL3HDAC3HDAC1HDAC2HDAC8
	SCHEMBL1024753	0.76	KDM4E (0.40)	HSD17B10MAPTKDM4EALDH1A1HPGD
	SCHEMBL1025402	0.73	AGPAT2 (0.47)	HDAC3HDAC1HDAC2HDAC8HDAC6
	SCHEMBL1025032	0.73	KDM4E (0.37)	TSHRHSD17B10MAPTKDM4EALDH1A1
	SCHEMBL12955409	0.72	AGPAT2 (0.42)	HDAC3HDAC1HDAC2HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.