Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.58 |
| ▸ | MGLL | Q99685 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | FAAH | O00519 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | XBP1 | P17861 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13113726 | 0.91 | PTGS1 (0.55) | ALDH1A1HTTKDM4EGAAPTGS1 | |
| SCHEMBL15606237 | 0.90 | PTGS1 (0.51) | ALDH1A1HTTKDM4EGAAPTGS1 | |
| SCHEMBL12848812 | 0.87 | ALDH1A1 (0.44) | ALDH1A1HTTKDM4EGAAPTGS1 | |
| SCHEMBL16862559 | 0.86 | PTGS1 (0.57) | ALDH1A1HTTKDM4EGAAPTGS1 | |
| SCHEMBL17841970 | 0.86 | PTGS1 (0.71) | ALDH1A1HTTKDM4EGAAPTGS1 | |
| SCHEMBL17841910 | 0.86 | PTGS1 (0.61) | ALDH1A1HTTKDM4EGAAPTGS1 | |
| SCHEMBL17739715 | 0.86 | PTGS1 (0.57) | ALDH1A1HTTKDM4EGAAPTGS1 | |
| SCHEMBL17739717 | 0.86 | PTGS1 (0.57) | ALDH1A1HTTKDM4EGAAPTGS1 | |
| SCHEMBL13077804 | 0.86 | PTGS1 (0.47) | ALDH1A1HTTKDM4EGAAPTGS1 | |
| SCHEMBL15354307 | 0.85 | PTGS1 (0.55) | ALDH1A1HTTKDM4EGAAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3466976-B1 | ANTI-HER2 ANTIBODY-DRUG CONJUGATE | DAIICHI SANKYO CO LTD (JP) | 2021-09-08 | — | — | EP | disclosed |
| WO-2014008375-A1 | TERMINALLY MODIFIED POLYMERS AND CONJUGATES THEREOF | MERSANA THERAPEUTICS, INC. (US) | 2014-01-09 | — | — | WO | disclosed |
| WO-2012016188-A2 | METHODS AND COMPOSITIONS FOR DELIVERY OF ACTIVE AGENTS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2012-02-02 | — | — | WO | disclosed |