SCHEMBL10283883

SCHEMBL10283883

CC1(C)CCOc2c(Cl)cc(CN3CCC4(CC3)CN(c3ccc(N5OCO5)cc3)C(=O)O4)cc21

nearest known ligand 0.77

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ SSTR5 P35346 20/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17612749 0.90 SSTR5 (0.81) SSTR5
SCHEMBL14963282 0.89 SSTR5 (0.82) SSTR5
SCHEMBL10283895 0.87 SSTR5 (1.00) SSTR5
SCHEMBL10284121 0.82 SSTR5 (0.55) SSTR5
SCHEMBL10284289 0.82 SSTR5 (0.82) SSTR5
SCHEMBL14963276 0.80 SSTR5 (0.82) SSTR5
SCHEMBL14963277 0.80 SSTR5 (0.82) SSTR5
SCHEMBL10283896 0.79 SSTR5 (0.77) SSTR5
SCHEMBL17612803 0.79 SSTR5 (0.85) SSTR5
SCHEMBL10283881 0.79 SSTR5 (1.00) SSTR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012024183-A1 SPIROXAZOLIDINONE COMPOUNDS MERCK SHARP & DOHME CORP. (US) 2012-02-23 — — WO disclosed
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