Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 19/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14963453 | 0.87 | SIGMAR1 (0.61) | SSTR5OPRM1SIGMAR1 | |
| SCHEMBL672565 | 0.85 | SSTR5 (0.73) | SSTR5 | |
| SCHEMBL10283883 | 0.82 | SSTR5 (0.77) | SSTR5 | |
| SCHEMBL10284128 | 0.82 | SSTR5 (0.67) | SSTR5 | |
| SCHEMBL14963454 | 0.80 | OPRM1 (0.57) | SSTR5OPRM1SIGMAR1 | |
| SCHEMBL10284066 | 0.80 | SSTR5 (0.77) | SSTR5OPRM1SIGMAR1 | |
| SCHEMBL10283896 | 0.79 | SSTR5 (0.77) | SSTR5OPRM1SIGMAR1 | |
| SCHEMBL14963449 | 0.78 | OPRM1 (0.58) | SSTR5OPRM1SIGMAR1 | |
| SCHEMBL14957252 | 0.78 | SSTR5 (0.71) | SSTR5 | |
| SCHEMBL671856 | 0.77 | SSTR5 (0.69) | SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012024183-A1 | SPIROXAZOLIDINONE COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2012-02-23 | — | — | WO | disclosed |