Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL835006 | 0.93 | TDP1 (0.48) | ALDH1A1HPGDGAAKDM4EMAPT | |
| SCHEMBL835274 | 0.93 | ALDH1A1 (0.51) | ALDH1A1HPGDGAAKDM4EMAPT | |
| SCHEMBL834181 | 0.93 | KMT2A (0.46) | ALDH1A1HPGDGAAKDM4EMAPT | |
| SCHEMBL835004 | 0.93 | TDP1 (0.48) | ALDH1A1HPGDGAAKDM4EMAPT | |
| SCHEMBL834180 | 0.93 | KMT2A (0.46) | ALDH1A1HPGDGAAKDM4EMAPT | |
| SCHEMBL835570 | 0.93 | ALDH1A1 (0.51) | ALDH1A1HPGDGAAKDM4EMAPT | |
| SCHEMBL835275 | 0.93 | ALDH1A1 (0.51) | ALDH1A1HPGDGAAKDM4EMAPT | |
| SCHEMBL834065 | 0.93 | KMT2A (0.46) | ALDH1A1HPGDGAAKDM4EMAPT | |
| SCHEMBL835005 | 0.93 | TDP1 (0.48) | ALDH1A1HPGDGAAKDM4EMAPT | |
| SCHEMBL12015308 | 0.93 | TDP1 (0.48) | ALDH1A1HPGDGAAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143446-B2 | Substituted acrylamide derivative and pharmaceutical composition comprising the same | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-03-27 | — | — | US | disclosed |