Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.34 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2795426 | 0.85 | MAPK14 (0.38) | MAPK14ALDH1A1KDM4EMAPK1HTT | |
| SCHEMBL10285280 | 0.84 | ALDH1A1 (0.48) | MAPK14ALDH1A1KDM4EMAPK1HTT | |
| SCHEMBL4302121 | 0.84 | MAPK14 (0.37) | MAPK14ALDH1A1KDM4EMAPK1HTT | |
| SCHEMBL14279585 | 0.82 | ALDH1A1 (0.37) | MAPK14ALDH1A1KDM4EMAPK1HTT | |
| SCHEMBL2796290 | 0.80 | NR4A2 (0.38) | MAPK14ALDH1A1KDM4EKMT2ADYRK1A | |
| SCHEMBL2799244 | 0.77 | MAPT (0.50) | ALDH1A1KMT2APTGER4TNFRSF1APDE5A | |
| SCHEMBL2796905 | 0.77 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPK1HTTHSD17B10 | |
| SCHEMBL12002245 | 0.76 | ALDH1A1 (0.55) | ALDH1A1KDM4EMAPK1HTTHSD17B10 | |
| SCHEMBL14279467 | 0.74 | KDM4E (0.34) | MAPK14ALDH1A1KDM4EMAPK1HTT | |
| SCHEMBL2797929 | 0.73 | KMT2A (0.48) | ALDH1A1HSD17B10KMT2APTGER4TNFRSF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2468743-A1 | Nitrogen-containing bicyclic compounds useful as antibacterial agents | Toyama Chemical Co., Ltd. (JP) | 2012-06-27 | — | — | EP | disclosed |