Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ILK | Q13418 | 19/20 | 0.79 |
| ▸ | GSK3B | P49841 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL687722 | 0.89 | ILK (1.00) | ILKGSK3B | |
| SCHEMBL687201 | 0.83 | ILK (0.76) | ILKGSK3B | |
| SCHEMBL686518 | 0.77 | ILK (1.00) | ILKGSK3B | |
| SCHEMBL686438 | 0.76 | ILK (1.00) | ILKGSK3B | |
| SCHEMBL687535 | 0.75 | ILK (1.00) | ILKGSK3B | |
| SCHEMBL687009 | 0.75 | ILK (1.00) | ILKGSK3B | |
| SCHEMBL686544 | 0.75 | ILK (0.76) | ILKGSK3B | |
| SCHEMBL687226 | 0.75 | ILK (1.00) | ILKGSK3B | |
| SCHEMBL686410 | 0.74 | ILK (1.00) | ILKGSK3B | |
| SCHEMBL686473 | 0.74 | ILK (0.76) | ILKGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1542997-B1 | PYRAZOLYLBENZOTHIAZOLE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | DERMIRA CANADA INC (CA) | 2012-02-29 | — | — | EP | disclosed |