Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL570861 | 0.85 | KDM4E (0.36) | PDE10AMAOBMAPTLMNAENPP2 | |
| SCHEMBL15065321 | 0.85 | MAPK14 (0.41) | MAPTLMNATP53 | |
| SCHEMBL15085771 | 0.84 | TNIK (0.33) | PDE10AMAOBMAPTLMNAENPP2 | |
| SCHEMBL569350 | 0.83 | HDAC1 (0.37) | PDE10AMAOBLMNA | |
| SCHEMBL15064441 | 0.82 | PDE1A (0.36) | PDE10AMAOBMAPTLMNAENPP2 | |
| SCHEMBL570302 | 0.79 | ALDH1A1 (0.40) | MAPTLMNATP53 | |
| SCHEMBL569886 | 0.77 | EGFR (0.35) | PDE10AMAPTLMNATP53 | |
| SCHEMBL10285695 | 0.77 | MEN1 (0.40) | PDE10AMAOBMAPTLMNA | |
| SCHEMBL15065151 | 0.76 | CYP1A2 (0.39) | LMNATP53 | |
| SCHEMBL15068355 | 0.76 | ALDH1A1 (0.41) | LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012018909-A1 | FUSED HETEROCYCLIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-02-09 | — | — | WO | disclosed |