Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 4/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.34 |
| ▸ | NAMPT | P43490 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1197884 | 0.99 | AHCY (0.43) | AHCYHDAC3HDAC6HDAC1HDAC8 | |
| Hydrochloric Acid SCHEMBL1026614 | 0.92 | AHCY (0.43) | AHCYHDAC3HDAC6HDAC1HDAC8 | |
| Hydrochloric Acid SCHEMBL1025161 | 0.90 | AHCY (0.42) | AHCYHDAC6HDAC1NAMPTHTT | |
| Hydrochloric Acid SCHEMBL1026640 | 0.82 | AHCY (0.42) | AHCYHDAC6HDAC1NAMPTHTT | |
| SCHEMBL1024888 | 0.81 | AHCY (0.38) | AHCYNAMPT | |
| SCHEMBL1026106 | 0.81 | AHCY (0.38) | AHCYHDAC3HDAC1HDAC2NAMPT | |
| SCHEMBL1023120 | 0.80 | AHCY (0.41) | AHCYSMN1; SMN2 | |
| SCHEMBL1026047 | 0.80 | AHCY (0.51) | AHCY | |
| SCHEMBL1026661 | 0.80 | AHCY (0.42) | AHCYHTTOPRM1 | |
| SCHEMBL1027043 | 0.78 | AHCY (0.39) | AHCYNAMPTOPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2275404-A1 | HOMOCYSTEINE SYNTHASE INHIBITOR | Mitsubishi Tanabe Pharma Corporation (JP) | 2011-01-19 | — | — | EP | disclosed |