Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.32 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 4/20 | 0.31 |
| ▸ | ACHE | P22303 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.30 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10286577 | 0.97 | BRD4 (0.34) | BRD4EPAS1NPSR1KDM4ETP53 | |
| SCHEMBL10286184 | 0.83 | BRD4 (0.44) | BRD4NPSR1SMN1; SMN2BCHEACHE | |
| SCHEMBL527692 | 0.80 | BRD4 (0.47) | BRD4NPSR1KDM4ESMN1; SMN2BCHE | |
| SCHEMBL10286171 | 0.79 | ALDH1A1 (0.44) | BRD4NPSR1KDM4EGAAACHE | |
| SCHEMBL14884970 | 0.77 | MAPT (0.38) | EPAS1NPSR1ALDH1A1MAPT | |
| SCHEMBL10286163 | 0.77 | ALDH1A1 (0.37) | BRD4KDM4ETP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL10286477 | 0.76 | ALDH1A1 (0.48) | BRD4NPSR1KDM4EGAAACHE | |
| SCHEMBL10286125 | 0.75 | BRD4 (0.35) | BRD4KDM4ESMN1; SMN2GAAACHE | |
| SCHEMBL10286121 | 0.75 | RXFP1 (0.42) | KDM4ESMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL10286579 | 0.74 | ALDH1A1 (0.40) | BRD4KDM4EGAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012001040-A1 | NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-05 | — | — | WO | disclosed |