SCHEMBL10286385

SCHEMBL10286385

C=CCOc1c(C)cnc2c1CCCC2O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
UGT2B17 O75795 2/20 0.33
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10286035 0.81 NPC1 (0.31)
SCHEMBL10286367 0.80 UGT2B17 (0.38) UGT2B17ACHE
SCHEMBL10286383 0.79 UGT2B17 (0.33) UGT2B17ACHE
SCHEMBL10286351 0.76 UGT2B17 (0.34) UGT2B17ACHE
SCHEMBL10286182 0.74 UGT2B17 (0.35) UGT2B17ACHE
SCHEMBL10287385 0.74 UGT2B17 (0.42) UGT2B17ACHE
SCHEMBL10286291 0.71 MAPT (0.34) UGT2B17ACHE
SCHEMBL6475145 0.70 DDB1 (0.41)
SCHEMBL23782941 0.70 UGT2B17 (0.33) UGT2B17ACHE
SCHEMBL17128342 0.70 UGT2B17 (0.33) UGT2B17ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130102631-A1 NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES SYNGENTA CROP PROTECTION LLC (US) 2013-04-25 US disclosed
US-20130102631-A1 NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES SYNGENTA CROP PROTECTION LLC (US) 2013-04-25 US disclosed
WO-2012001040-A1 NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2012-01-05 WO disclosed
EP-0187977-B1 TETRAHYDROQUINOLINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND ANTI-PEPTIC ULCER COMPOSITIONS CONTAING THE SAME OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1990-08-29 EP disclosed
US-4880815-A GASTRIC JUICE INHIBITORS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1989-11-14 US disclosed
US-4738970-A Benzimidazolyl-thio-tetrahydroquinolines and anti-peptic ulcer compositions containing the same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1988-04-19 US disclosed
EP-0187977-A1 Tetrahydroquinoline derivatives, process for preparing the same and anti-peptic ulcer compositions containg the same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1986-07-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130102631-A1 NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES MSR1, DDT, MPO UGT2B17 1446/4885ACHE 660/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.