Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 14/20 | 0.57 |
| ▸ | NPC1 | O15118 | 13/20 | 0.57 |
| ▸ | MEN1 | O00255 | 13/20 | 0.57 |
| ▸ | RAB9A | P51151 | 12/20 | 0.57 |
| ▸ | CASP3 | P42574 | 4/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.50 |
| ▸ | HTT | P42858 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10286990 | 0.81 | NPC1 (0.67) | KMT2ANPC1MEN1RAB9ACASP3 | |
| SCHEMBL10253378 | 0.80 | NPC1 (0.76) | KMT2ANPC1MEN1RAB9ACASP3 | |
| SCHEMBL27134428 | 0.77 | NPC1 (0.62) | KMT2ANPC1MEN1RAB9AHPGD | |
| SCHEMBL5836867 | 0.77 | CDK2 (0.61) | KMT2ANPC1MEN1RAB9ACASP3 | |
| SCHEMBL375564 | 0.76 | NPC1 (0.69) | KMT2ANPC1MEN1RAB9ASMN1; SMN2 | |
| SCHEMBL24073708 | 0.75 | KDR (0.64) | KMT2ANPC1MEN1RAB9ACASP3 | |
| SCHEMBL25063129 | 0.74 | CSNK2A2 (0.53) | KMT2ANPC1MEN1RAB9ASMN1; SMN2 | |
| SCHEMBL24072715 | 0.73 | TRPV1 (0.45) | KMT2ANPC1MEN1RAB9ASMN1; SMN2 | |
| SCHEMBL12697305 | 0.72 | MEN1 (0.50) | KMT2AMEN1LMNAMAPT | |
| SCHEMBL19632762 | 0.72 | STAT3 (0.61) | KMT2ANPC1MEN1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120010187-A1 | BROAD SPECTRUM BENZOTHIOPHENE-NITROTHIAZOLIDE AND OTHER ANTIMICROBIALS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010187-A1 | BROAD SPECTRUM BENZOTHIOPHENE-NITROTHIAZOLIDE AND OTHER ANTIMICROBIALS | NMT1, MLEC, EPN1 | KMT2A 4279/4885NPC1 3834/4885MEN1 2908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.