Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.38 |
| ▸ | HPGD | P15428 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10288199 | 0.93 | LMNA (0.41) | LMNAALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL10288139 | 0.89 | PIK3CA (0.38) | LMNAALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL10288850 | 0.88 | LMNA (0.42) | LMNAALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL10006034 | 0.88 | PIK3CA (0.42) | LMNAALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL10288200 | 0.86 | SLC6A2 (0.45) | LMNAALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL626440 | 0.81 | PIK3CA (0.43) | LMNAALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL622983 | 0.76 | PIK3CA (0.43) | LMNAALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL10298538 | 0.76 | PIK3CA (0.36) | LMNAALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL10006010 | 0.76 | PIK3CA (0.51) | LMNAALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL10288203 | 0.75 | SLC6A2 (0.49) | LMNAALDH1A1HSD17B10GAAPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012021696-A1 | HETEROARYLS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2012-02-16 | — | — | WO | disclosed |