Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 8/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | AVPR1B | P47901 | 3/20 | 0.33 |
| ▸ | ACACB | O00763 | 3/20 | 0.32 |
| ▸ | ACACA | Q13085 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9114523 | 0.87 | ACACB (0.37) | ACACBACACA | |
| SCHEMBL9110349 | 0.83 | ACACB (0.37) | TLR9TLR7ACACBACACAMAPT | |
| SCHEMBL9114322 | 0.83 | ACACB (0.43) | ACACBACACA | |
| SCHEMBL16622800 | 0.82 | ACACB (0.37) | ACACBACACA | |
| SCHEMBL9112166 | 0.79 | ACACB (0.43) | ACACBACACA | |
| SCHEMBL9114057 | 0.75 | ACACB (0.44) | ACACBACACA | |
| SCHEMBL9111735 | 0.75 | ACACB (0.51) | ACACBACACA | |
| SCHEMBL9111726 | 0.74 | ACACB (0.41) | ACACBACACA | |
| SCHEMBL9111718 | 0.74 | ACACB (0.41) | ACACBACACA | |
| SCHEMBL9112940 | 0.74 | ACACA (0.44) | ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012074126-A1 | BICYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-06-07 | — | — | WO | disclosed |