SCHEMBL10288992

SCHEMBL10288992

CCN1CCC(CN2C(=O)C3(COc4cc(O)c(O)cc43)c3ccccc32)CC1

nearest known ligand 0.52

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 19/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10289017 0.92 SCN9A (0.48) SCN9A
SCHEMBL10289481 0.90 SCN9A (0.53) SCN9A
SCHEMBL328306 0.89 SCN9A (0.64) SCN9A
SCHEMBL10289001 0.88 SCN9A (0.48) SCN9A
SCHEMBL10289095 0.88 SCN9A (0.49) SCN9A
SCHEMBL10289194 0.88 SCN9A (0.48) SCN9A
Hydrochloric Acid SCHEMBL281729 0.88 SCN9A (0.63) SCN9A
SCHEMBL10289484 0.86 SCN9A (0.51) SCN9A
SCHEMBL3330744 0.85 SCN9A (0.49) SCN9A
SCHEMBL10289269 0.85 SCN9A (0.48) SCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1888595-B1 SPIRO-OXINDOLE COMPOUNDS AND THEIR USES AS THERAPEUTIC AGENTS XENON PHARMACEUTICALS INC (CA) 2012-02-01 EP disclosed