Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14221062 | 0.92 | SCN9A (0.45) | SCN9A | |
| SCHEMBL10288992 | 0.90 | SCN9A (0.52) | SCN9A | |
| SCHEMBL10289017 | 0.90 | SCN9A (0.48) | SCN9A | |
| SCHEMBL10289194 | 0.90 | SCN9A (0.48) | SCN9A | |
| SCHEMBL12314867 | 0.89 | SCN9A (0.67) | SCN9A | |
| SCHEMBL10289001 | 0.88 | SCN9A (0.48) | SCN9A | |
| SCHEMBL12314862 | 0.88 | SCN9A (0.58) | SCN9A | |
| Hydrochloric Acid SCHEMBL2304101 | 0.88 | SCN9A (0.66) | SCN9A | |
| SCHEMBL328189 | 0.88 | SCN9A (0.66) | SCN9A | |
| SCHEMBL10289484 | 0.88 | SCN9A (0.51) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888595-B1 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC (CA) | 2012-02-01 | — | — | EP | disclosed |