Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR55 | Q9Y2T6 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16921578 | 0.87 | BRAF (0.36) | GPR55CNR2BRAFMAP2K1CNR1 | |
| SCHEMBL755237 | 0.84 | CNR2 (0.39) | GPR55CNR2HCAR2CNR1LMNA | |
| SCHEMBL10290270 | 0.84 | CNR2 (0.39) | GPR55CNR2BRAFMAP2K1HCAR2 | |
| SCHEMBL27844397 | 0.82 | GPR55 (0.38) | GPR55CNR2BRAFMAP2K1HCAR2 | |
| SCHEMBL10290074 | 0.72 | CNR2 (0.35) | GPR55CNR2BRAFMAP2K1HCAR2 | |
| SCHEMBL16921550 | 0.70 | CNR2 (0.40) | GPR55CNR2BRAFMAP2K1CNR1 | |
| SCHEMBL2484216 | 0.69 | CNR2 (0.37) | GPR55CNR2BRAFMAP2K1CNR1 | |
| SCHEMBL764336 | 0.67 | NPSR1 (0.36) | GPR55CNR2BRAFMAP2K1CNR1 | |
| SCHEMBL10290766 | 0.66 | CNR2 (0.44) | GPR55CNR2HCAR2CNR1LMNA | |
| SCHEMBL755219 | 0.66 | CNR2 (0.44) | GPR55CNR2HCAR2CNR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1422218-B1 | ANTIVIRAL AGENT | SHIONOGI & CO (JP) | 2012-03-21 | — | — | EP | disclosed |