SCHEMBL10290484

SCHEMBL10290484

CN(C)c1nccc(-c2c(-c3ccc(F)cc3)nn3c2COCC3)n1

nearest known ligand 0.66

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CSNK1D P48730 3/20 0.66
MAPK14 Q16539 8/20 0.52
MAPK13 O15264 2/20 0.52
MAPK12 P53778 2/20 0.52
MAPK11 Q15759 2/20 0.52
ACVR1 Q04771 8/20 0.47
THRB P10828 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10290480 0.85 CSNK1D (0.75) CSNK1DMAPK14MAPK13MAPK12MAPK11
SCHEMBL10290857 0.84 THRB (0.56) CSNK1DMAPK14MAPK13MAPK12MAPK11
SCHEMBL3108242 0.83 CSNK1D (0.71) CSNK1DMAPK14MAPK13MAPK12MAPK11
SCHEMBL10290479 0.83 CSNK1D (0.71) CSNK1DMAPK14MAPK13MAPK12MAPK11
SCHEMBL10290371 0.83 THRB (0.52) CSNK1DMAPK14MAPK13MAPK12MAPK11
SCHEMBL3091618 0.81 CSNK1D (0.93) CSNK1DMAPK14MAPK13MAPK12MAPK11
SCHEMBL10290481 0.79 CSNK1D (0.90) CSNK1DMAPK14MAPK13MAPK12MAPK11
SCHEMBL3110779 0.79 CSNK1D (0.66) CSNK1DMAPK14MAPK13MAPK12MAPK11
SCHEMBL25225084 0.77 MAPK14 (0.59) CSNK1DMAPK14MAPK13MAPK12MAPK11
SCHEMBL19806169 0.76 CSNK1D (0.55) CSNK1DMAPK14MAPK13MAPK12MAPK11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2409570-A2 Fungicidal mixtures based on pyrazolopyridine compounds BASF SE (DE) 2012-01-25 EP disclosed